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Laboratory of Molecular Pathology

Laboratory of Molecular Pathology



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Doctor Screpanti is, since 1999, Professor of General Pathology in the Medical School of the Faculty of Medicine and Surgery of the University "La Sapienza" of Rome, Italy.


1. Analysis of cellular and molecular mechanisms involved in T cell differentiation through the generation of in vivo and in vitro experimental models;
2. Characterization of the molecular events involved in T cell leukemogenesis, mainly focusing on generating transgenic mice useful to understand the role of deregulated Notch signaling in sustaining development and progression of T cell Acute Lymphoblastic Leukemia;
3. Identification of molecular markers of Lymphoid Leukemias, susceptible to become therapeutic targets 

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