Vittorio Loffredo
University position
DottorandoInterests
Education & Work experience July 2018 – To date - PhD student in Behavioral Neuroscience at University of Rome “La Sapienza” and Istituto di Biologia Cellulare e Neurobiologia (IBCN-CNR), National Research Council, Monterotondo, Rome (Italy) at Elvira De Leonibus’ lab. November 2016 – July 2018 - PhD student in Behavioral Neuroscience at University of Rome “La Sapienza” and Institute of Genetics and Biophysics (IGB) “Adriano Buzzati-Traverso”, National Research Council, Naples (Italy) at Elvira De Leonibus’ lab. April 2014 - October 2016 - Research Fellowship at Telethon Institute of Genetics and Medicine (TIGEM), Pozzuoli (Naples, Italy) October 2013 - April 2014 - Internal stage at Pharmacy Department of University of Naples “Federico II”, Naples (Italy) at Giuseppe De Rosa’s lab. November 2011 – February 2013 - Professional training at internal pharmacy of Hospital “San Gennaro dei poveri”, Naples (Italy) 2008-2013 - Master’s Degree in Pharmacy at University of Naples “Federico II”, Naples (Italy).Thesis: Self-assembling nanoparticles containing Zoledronic Acid for the treatment of glioblastoma. Oral communications Oral presentation at SINS PhD Meeting in Neuroscience: "New perspectives in Neuroscience: The Researches of Young Italian Neuroscientists”, March 1st 2019, Naples (Italy).Title: Sex differences shape memory capacity decline during ageing.Authors: Vittorio Loffredo, Giulia Torromino, Federica Esposito, Martina Colucci, Maria De Risi, Antonino La Rocca Elvira De Leonibus Oral presentation at Telethon Institute of Genetics and Medicine (TIGEM) Data Club, April 17th 2018, Pozzuoli (NA), Italy; Title: Sex differences in memory capacity: a neuronal circuit issue?Authors: Vittorio Loffredo, Giulia Torromino, Federica Esposito, Martina Colucci, Maria De Risi, Elvira De Leonibus Oral presentation at SINS PhD Meeting in Neuroscience: "New perspectives in Neuroscience: The Researches of Young Italian Neuroscientists”, February 23rd 2018, Naples (Italy).Title: Sex differences regulate memory capacity during ageing.Authors: Vittorio Loffredo, Giulia Torromino, Federica Esposito, Martina Colucci, Elvira De Leonibus Oral presentation at Institute of Genetics and Biophysics (IGB) PhD Retreat, April 6th 2017, Naples (Italy).Title: Sex regulates memory capacity.Authors: Vittorio Loffredo, Giulia Torromino, Federica Esposito, Anna Carboncino, Anna Cecere, Andrea Mele, Elvira De Leonibus List of poster presentations Poster presentation @ 11th FENS Forum of Neuroscience 2018, Berlin, Germany; Title: Sex differences regulate memory capacity during ageing; Authors: Loffredo V., Torromino G., Esposito F., Colucci M., De Risi M., De Leonibus E. Poster presentation at SINS PhD Meeting in Neuroscience: "New perspectives in Neuroscience: The Researches of Young Italian Neuroscientists”, February 24th 2017, Naples (Italy).Title: Sex regulates memory capacity.Authors: Vittorio Loffredo, Giulia Torromino, Federica Esposito, Anna Carboncino, Anna Cecere, Andrea Mele, Elvira De Leonibus Professional skills Laboratory equipments: UV/Vis spectrophotometer, Spectrofluorimeter, High Performance Liquid Cromatography (HPLC), Photon Correlation Spectroscopy (PCS), M3/PALS for z-potential measuring, Laser Light Scattering, nanoparticles extruder, Rotavapor, Ultrasonicators, Liophilyzers, Centrifuges and ultracentrifuges, Optical microscope, Fluorescence microscopes (Leica DM6000; Leica DMI6000; Nikon NiU), Confocal microscopes (Zeiss LSM 700/710; Nikon A1), Cryostat, Vibratome, Microtome, Chemidoc, Dark chamber. Laboratory techniques: Nanoparticles assembling, Cell cultures, Western Blot analysis, PCR, DNA digestion, purification and cloning, Cells and tissues DNA extraction, Enzyme assays, Bacterial cultures, Lysosomes extraction and purification from cell cultures, Cell cultures and tissues immunofluorescence, Immunoistochemistry, Optogenetics. In vivo laboratory techniques: Behavioral tasks (6 Different and Identical Object Recognition Task, Rotarod, Hanging wire, Hanging steel), Animals handling (Mus musculus, CD1 and C57), IP injections, transcardiac perfusion, Brain and other organs sample.