Technology and science are usually considered distinct disciplines. In this Course it will be shown that science is a key ingredient for developing new techniques and conversely technology is important for modern science to make new discoveries. Particular emphasis will be given to space missions and high energy physics experiment where aerospace materials are often used because of their high mechanical characteristics. Another part of the course is devoted to the technology of composite materials and to non destructive testing. The content of the Course includes : Use of non destructive testing for checking structural integrity of space structures manufactured in metallic and composite materials, Holographic interferometry as a non destructive technique, Practical problems of space missions from the structural and technological point of view (satellites, interplanetary probes and international space station) through real cases of space missions in which the School of Aerospace Engineering has been fully involved.