Publications

   Scopus

Recent Publications (Last 10 years)

  1. Ferretti E. and Po, A. Interrogating molecular data for medulloblastoma risk stratification. 2018. The Lancet Oncology. doi:10.1016/S1470-2045(18)30585-0.
  1. Besharat Z.M., Sabato, C., Po A., Gianno F., Abballe L., Napolitano M., Miele E., Giangaspero F., Vacca A., Catanzaro G., Ferretti E. Low expression of miR-466f-3p sustains epithelial to mesenchymal transition in Sonic Hedegehog medulloblastoma stem cells through Vegfa-Nrp2 signaling pathway. Frontiers in Pharmacology. 2018;9:1281. doi: 10.3389/fphar.2018.01281.
  1. Abballe L., Mastronuzzi A., Miele E., Carai A., Besharat Z.M., Moretti M., De Smaele E., Giangaspero F., Locatelli F., Ferretti E. and Po A. Numb Isoforms Deregulation in Medulloblastoma and Role of p66 Isoform in Cancer and Neural Stem Cells. Frontiers in Pediatrics. 2018, 6:315. doi: 10.3389/fped.2018.00315.
  1. Gianno F., Antonelli M., Ferretti E., Massimino M., Arcella A. and Giangaspero F. Pediatric high-grade glioma: A heterogeneous group of neoplasms with different molecular drivers. Glioma, 2018 1(4), p.117.
  1. Gasparri M.L., Besharat Z.M., Farooqi A.A., Khalid S., Taghavi K., Besharat R.A., Sabato C., Papadia A., Panici P.B., Mueller M.D. and Ferretti E. MiRNAs and their interplay with PI3K/AKT/mTOR pathway in ovarian cancer cells: a potential role in platinum resistance. Journal of Cancer Research and Clinical Oncology, 2018, pp.1-6. doi: 10.1007/s00432-018-2737-y.
  1. Po A., Abballe L., Sabato C., Gianno F., Chiacchiarini M., Catanzaro G., De Smaele E., Giangaspero F., Ferretti E., Miele E., Besharat Z.M. Sonic Hedgehog Medulloblastoma Cancer Stem Cells Mirnome and Transcriptome Highlight Novel Functional Networks. Int. J. Mol. Sci. 2018, 19, 2326. doi: 10.3390/ijms19082326.
  1. Catanzaro G., Besharat Z.M., Chiacchiarini M., Abballe L., Sabato C., Vacca A., Borgiani P., Dotta F., Tesauro M., Po A., Ferretti E. Circulating MicroRNAs in Elderly Type 2 Diabetic Patients. International Journal of Endocrinology. vol. 2018, Article ID 6872635, 11 pages, 2018. doi:10.1155/2018/6872635.
  1. Orlando D., Miele E., De Angelis B., Guercio M., Boffa I., Sinibaldi M., Po A., Caruana I., Abballe L., Carai A., Caruso S., Camera A., Moseley A., Hagedoorn S.R., Heemskerk M.H.M., Giangaspero F., Mastronuzzi A., Ferretti E., Locatelli F., Quintarelli C. Adoptive immunotherapy using PRAME-specific T cells in medulloblastoma. Cancer research. 2018 Jan 1:canres-3140.
  1. Storniolo A, Alfano V, Carbotta S, Ferretti E, Di Renzo L. IRE1α deficiency promotes tumor cell death and eIF2α degradation through PERK dipendent autophagy. Cell Death Discov. 2018 Jan 29;4:3. doi: 10.1038/s41420-017-0002-9
  1. Mellini P., Marrocco B., Borovika D., Polletta L., Carnevale I., Saladini S., Stazi G., Zwergel C., Trapencieris P., Ferretti E. and Tafani M., 2018. Pyrazole-based inhibitors of enhancer of zeste homologue 2 induce apoptosis and autophagy in cancer cells. Phil. Trans. R. Soc. B, 373(1748), p.20170150.
  1. Besharat Z.M., Abballe L., Cicconardi F., Bhutkar A., Grassi L., Le Pera L., Moretti M., Chinappi M., D’Andrea D., Mastronuzzi A., Ianari A., Vacca A., De Smaele E., Locatelli F., Po A., Miele E., Ferretti E. 2018. Foxm1 controls a pro-stemness microRNA network in neural stem cells. Scientific reports, 8(1), p.3523.
  1. Infante P., Faedda R., Bernardi F., Bufalieri F., Severini L.L., Alfonsi R., Mazzà D., Siler M., Coni S., Po A., Petroni M., Ferretti E., Mori M., De Smaele E., Canettieri G., Capalbo C., Maroder M., Screpanti I., Kool M., Pfister M.S., Guardavaccaro D., Gulino A., Di Marcotullio L. 2018. Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis. Nature communications, 9(1), p.976.  
  1. Catanzaro G., Besharat Z.M., Miele E., Chiacchiarini M., Po A., Carai A., Marras C.E., Antonelli M., Badiali M., Raso A., Mascelli S., Schrimpf D., Stichel D., Tartaglia M., Capper D., von Deimling A., Giangaspero F., Mastronuzzi A., Locatelli F., Ferretti E. The miR-139-5p regulates proliferation of supratentorial paediatric low-grade gliomas by targeting the PI3K/AKT/mTORC1 signalling. Neuropathology and Applied Neurobiology 2018. doi: 10.1111/nan.12479.
  1. Bisicchia E, Sasso V, Catanzaro G, Leuti A, Besharat ZM, Chiacchiarini M, Molinari M, Ferretti E, Viscomi MT, Chiurchiù V. Resolvin D1 Halts Remote Neuroinflammation and Improves Functional Recovery after Focal Brain Damage Via ALX/FPR2 Receptor-Regulated MicroRNAs. Molecular Neurobiology. 2018:1-2. doi: https://doi.org/10.1007/s12035-018-0889-z.
  1. Catanzaro G, Sabato C, Russo M, Rosa A, Abballe L, Besharat ZM, Po A, Miele E, Bellavia D, Chiacchiarini M, Gessi M, Peruzzi G, Napolitano M, Antonelli M, Mastronuzzi A, Giangaspero F, Locatelli F, Screpanti I, Vacca A, Ferretti E. Loss of miR-107, miR-181c and miR-29a-3p Promote Activation of Notch2 Signaling in Pediatric High-Grade Gliomas (pHGGs). International journal of molecular sciences. 2017 Dec 17;18(12):2742. doi:10.3390/ijms18122742.
  1. Miele E, Valente S, Alfano V, Silvano M, Mellini P, Borovika D, Marrocco B, Po A, Besharat ZM, Catanzaro G, Battaglia G, Abballe L, Zwergel C, Stazi G, Milite C, Castellano S, Tafani M, Trapencieris P, Mai A, Ferretti E. The histone methyltransferase EZH2 as a druggable target in SHH medulloblastoma cancer stem cells. Oncotarget. 2017. doi: https://doi.org/10.18632/oncotarget.19782.
  1. Miele E, Po A, Begalli F, Antonucci L, Mastronuzzi A, Marras CE, Carai A,  Cucchi D, Abballe L, Besharat ZM, Catanzaro G, Infante P, Di Marcotullio L, Canettieri G, De Smaele E, Screpanti I, Locatelli F, Ferretti E. β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma Cancer Stem Cells. BMC Cancer. 2017. doi: 10.1186/s12885-017-3477-0 .
  1. Gasparri ML, Casorelli A, Bardhi E, Besharat AR, Savone D, Ruscito I, Farooqi AA, Papadia A, Mueller MD, Ferretti E, Benedetti Panici P. Beyond circulating microRNA biomarkers: Urinary microRNAs in ovarian and breast cancer. Tumour Biol. 2017 May;39(5):1010428317695525. doi: 10.1177/1010428317695525.
  1. Po A., Silvano M., Miele E., Capalbo C., Eramo A., Salvati V., Todaro M., Besharat Z.M., Catanzaro G., Cucchi D., Coni S., Di Marcotullio L., Canettieri G., Vacca A., Stassi G., De Smaele E., Tartaglia M., Screpanti I., De Maria R. and Ferretti E. Noncanonical GLI1 signalling promotes stemness features and in-vivo growth in lung adenocarcinoma. Oncogene 2017. doi:10.1038/onc.2017.91
  1. Laneve P., Po A., Favia A., Legnini I., Alfano V., Rea J., Di Carlo V., Bevilacqua V., Miele E., Mastronuzzi A., Carai A., Locatelli F., Bozzoni I., Ferretti E.* and Caffarelli E.* (*Share senior Authorship and co-corresponding). The long noncoding RNA linc-NeD125 controls the expression of medulloblastoma driver genes by microRNA sponge activity. Oncotarget 2017. doi: 10.18632/oncotarget.16049.
  1. Po A., Begalli F., Abballe L., Alfano V., Besharat Z.M., Catanzaro G., Vacca A., Napolitano M., Tafani M., Giangaspero F., Locatelli F., Ferretti E.* and Miele E.* (*Share senior Authorship and co-corresponding). ß-arrestin1/miR-326 transcription unit is epigenetically regulated in Neural Stem Cells where it controls stemness and growth arrest. 2017 Stem Cell International. doi: 10.1155/2017/5274171.
  1. Coni S., Mancuso A.B., Di Magno L., Sdruscia G., Manni S., Serrao S.M., Rotili D., Mai A., Spiombi E., Bufalieri F., Petroni M., Desmaele E., Ferretti E., Capalbo C., Kusio-Kobiałka M., Screpanti I., Di Marcotullio L., Canettieri G. Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma. 2017 Scientific Reports. doi: 10.1038/srep44079.  
  1. Catanzaro G., Curcio M., Cirillo G., Spizzirri U.G., Besharat Z.M., Abballe L., Vacca A., Iemma F., Picci N., Ferretti E. Albumin nanoparticles for glutathione-responsive release of cisplatin: New opportunities for medulloblastoma. Int J Pharm. 2017 Jan 30;517(1-2):168-174. doi: 10.1016/j.ijpharm.2016.12.017.
  1. Micheli, F., Palermo, R., Talora, C., Ferretti, E., Vacca, A. and Napolitano, M., 2016. Regulation of proapoptotic proteins Bak1 and p53 by miR-125b in an experimental model of Alzheimer's disease: protective role of 17β− Estradiol. Neuroscience letters.
  1. Di Giannatale, A., Carai, A., Cacchione, A., Marrazzo, A., Dell’Anna, V.A., Colafati, G.S., Diomedi-Camassei, F., Miele, E., Po, A., Ferretti, E. and Locatelli, F., 2016. Anomalous vascularization in a Wnt medulloblastoma: a case report. BMC neurology, 16(1), p.103.
  1. Folgiero V, Miele E, Carai A, Ferretti E, Alfano V, Po A, Bertaina V, Goffredo BM, Benedetti MC, Diomedi Camassei F, Cacchione A, Locatelli F, Mastronuzzi A. IDO1 involvement in mTOR pathway: A molecular mechanism of resistance to mTOR targeting in medulloblastoma. Oncotarget. 2016 May 11; Advanced publication. doi: 10.18632/oncotarget.9284
  1. Di Magno L, Basile A, Coni S, Manni S, Sdruscia G, D'Amico D, Antonucci L, Infante P, De Smaele E, Cucchi D, Ferretti E, Di Marcotullio L, Screpanti I, Canettieri G. The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint. Oncotarget. 2016 Feb 23;7(8):9538-49. doi: 10.18632/oncotarget.7070.
  1. Catanzaro G, Besharat ZM, Garg N, Ronci M, Pieroni L, Miele E, Mastronuzzi A, Carai A, Alfano V, Po A, Screpanti I, Locatelli F, Urbani A, Ferretti E. MicroRNAs-proteomic networks characterizing human medulloblastoma-SLCs. Stem Cells International. Volume 2016 (2016) Article ID 2683042, 10 pages. http://dx.doi.org/10.1155/2016/2683042.
  1. Cefalo MG, Carai A, Miele E, Po A, Ferretti E, Mastronuzzi A, Germano IM. Human iPSC for Therapeutic Approaches to the Nervous System: Present and Future Applications. Stem Cells International. Volume 2016; 2016, Article ID 4869071, 11 pages. doi:10.1155/2016/4869071.
  1. Moavero R, Folgiero V, Carai A, Miele E, Ferretti E, Po A, Diomedi Camassei F, Lepri FR, Vigevano F, Curatolo P, Valeriani M, Colafati GS, Locatelli F, Tornesello A, Mastronuzzi A. Metastatic Group 3 Medulloblastoma in a Patient With Tuberous Sclerosis Complex: Case Description and Molecular Characterization of the Tumor. Pediatr Blood Cancer. 2016 Apr;63(4):719-22. doi: 10.1002/pbc.25851. Epub 2015 Dec 2.
  1. D'Amico D, Antonucci L, Di Magno L, Coni S, Sdruscia G, Macone A, Miele E, Infante P, Di Marcotullio L, De Smaele E, Ferretti E, Ciapponi L, Giangaspero F, Yates JR 3rd, Agostinelli E, Cardinali B, Screpanti I, Gulino A, Canettieri G. Non-canonical Hedgehog/AMPK-Mediated Control of Polyamine Metabolism Supports Neuronal and Medulloblastoma Cell Growth. Dev Cell. 2015 Oct 12;35(1):21-35. doi: 10.1016/j.devcel.2015.09.008.
  1. Miele E, Mastronuzzi A, Po A, Carai A, Alfano V, Serra A, Colafati GS, Strocchio L, Antonelli M, Buttarelli FR, Zani M, Ferraro S, Buffone A, Vacca A, Screpanti I, Giangaspero F, Giannini G, Locatelli F, Ferretti E. Characterization of medulloblastoma in Fanconi Anemia: a novel mutation in the BRCA2 gene and SHH molecular subgroup. Biomark Res. 2015 Jun; 3:13.
  1. Ronci M, Catanzaro G, Pieroni L, Po A, Besharat ZM, Greco V, Levi Mortera S, Screpanti I, Ferretti E*, Urbani A* (*co-corresponding). Proteomic analysis of human sonic hedgehog (SHH) medulloblastoma stem-like cells. Mol Biosyst. 2015. DOI: 10.1039/C5MB00034C.
  1. Anastasiadou E, Garg N, Bigi R, Yadav S, Campese AF, Lapenta C, Spada M, Cuomo L, Botta A, Belardelli F, Frati L, Ferretti E, Faggioni A, Trivedi P. Epstein-Barr virus infection induces miR-21 in terminally differentiated malignant B cells. Int J Cancer. 2015 Feb 20. doi: 10.1002/ijc.29489.
  2. Infante P, Mori M, Alfonfi R, Ghirga F, Aiello F, Toscano S, Ingallina C, Siler M, Cucchi D, Po A, Miele E, D’Amico D, Canettieri G, De Smaele E, Ferretti E, Screpanti I, Uccello Barretta G, Botta M, Botta B, Gulino A, Di Marcotullio L. Gli1/DNA interaction is druggable target for Hedgehog-dependent tumors. EMBO J. 2015. 34, 200-217. doi: 10.15252/embj.201489213.
  3. Del Bufalo F, Carai A, Figà-Talamanca L, Pettorini B, Mallucci C, Giangaspero F, Antonelli M, Badiali M, Moi L, Bianco G, Cacchione A, Locatelli F, Ferretti E*, Mastronuzzi A (*corresponding). Response of recurrent BRAFV600E mutated ganglioglioma to Vemurafenib as single agent. J Transl Med. 2014. Dec 19;12:356. doi: 10.1186/s12967-014-0356-1.
  4. Sebastiani G, Po A, Miele E, Ventriglia G, Ceccarelli E, Bugliani M, Marselli L, Marchetti P, Gulino A, Ferretti E*, Dotta F* (*Share senior Authorship). MicroRNA-124a is hyperexpressed in type-2 diabetic human pancreatic islets and negatively regulates insulin secretion. Acta Diabetol. 2015 Jun;52(3):523-30. doi: 10.1007/s00592-014-0675-y. Epub 2014 Nov 19.
  5. Di Magno L, Manzi D, D’Amico D, Coni S, Macone A, Infante P, Di Marcotullio L, De Smaele E, Ferretti E, Screpanti I, Agostinelli E, Gulino A, Canettieri G. Druggable glycolytic requirement for Hedgehog-dependent neuronal and medulloblastoma growth. Cell Cycle. 2014 Nov;13(21):3404-13.
  1. Mastronuzzi A, Miele E, Po A, Antonelli M, Buttarelli FR, Colafati GS, Del Bufalo F, Faedda R, Spinelli GP, Carai A, Giangaspero F, Gulino A, Locatelli F, Ferretti E. Large cell anaplastic medulloblastoma metastatic to the scalp: tumor and derived stem-like cells features. BMC Cancer. 2014 Apr 16;14(1):262.
  2. Kumar V, Palermo R, Talora C, Campese AF, Checquolo S, Bellavia D, Tottone L, Testa G, Miele E, Indraccolo S, Amadori A, Ferretti E, Gulino A, Vacca A, Screpanti I. Notch and NF-kB signaling pathways regulate miR-223/FBXW7 axis in T-cell acute lymphoblastic leukemia. Leukemia. 2014 Apr 14.
  3. Miele E, Buttarelli FR, Arcella A, Begalli F, Garg N, Silvano M, Po A, Baldi C, Carissimo G, Antonelli M, Spinelli GP, Capalbo C, Donofrio V, Morra I, Nozza P, Gulino A, Giangaspero F, Ferretti E. High-throughput microRNA profiling of pediatric high-grade gliomas. Neuro Oncol. 2014 Jan;16 (2):228-40.
  4. Valente S, Liu Y, Schnekenburger M, Zwergel C, Cosconati S, Gros C, Tardugno M, Labella D, Florean C, Minden S, Hashimoto H, Chang Y, Zhang X, Kirsch G, Novellino E, Arimondo PB, Miele E, Ferretti E, Gulino A, Diederich M, Cheng X, Mai A. Selective Non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells. J Med Chem. 2014 Feb 13;57(3):701-13.
  5. Garg N, Po A, Miele E, Campese AF, Begalli F, Silvano M, Infante P, Capalbo C, De Smaele E, Canettieri G, Di Marcotullio L, Screpanti I, Ferretti E*, Gulino A* (*co-corresponding). microRNA-17-92 cluster is a direct Nanog target and controls neural stem cell through Trp53inp1. EMBO J. 2013 Oct 30;32(21):2819-32.
  1. Mazzà D, Infante P, Colicchia V, Greco A, Alfonsi R, Siler M, Antonucci L, Po A, De Smaele E, Ferretti E, Capalbo C, Bellavia D, Canettieri G, Giannini G, Screpanti I, Gulino A, Di Marcotullio L. PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress. Cell Death Differ. 2013 Dec;20(12):1688-97.
  2. Rosato P, Anastasiadou E, Garg N, Lenze D, Boccellato F, Vincenti S, Severa M, Coccia EM, Bigi R, Cirone M, Ferretti E, Campese AF, Hummel M, Frati L, Presutti C, Faggioni A, Trivedi P. Differential regulation of miR-21 and miR-146a by Epstein-Barr virus-encoded EBNA2. Leukemia. 2012 Nov;26(11):2343-52.
  3. Miele E, Spinelli GP, Miele E, Di Fabrizio E, Ferretti E, Tomao S, Gulino A. Nanoparticle-based delivery of small interfering RNA: challenges for cancer therapy. Int J Nanomedicine. 2012;7:3637-57.
  1. Russo D, Scipioni A, Durante C, Ferretti E, Gandini L, Maggisano V, Paoli D, Verrienti A, Costante G, Lenzi A, Filetti S. Expression and localization of the sodium/iodide symporter (NIS) in testicular cells. Endocrine. 2011 Aug;40(1):35-40.
  2. De Smaele E, Di Marcotullio L, Moretti M, Pelloni M, Occhione MA, Infante P, Cucchi D, Greco A, Pietrosanti L, Todorovic J, Coni S, Canettieri G, Ferretti E, Bei R, Maroder M, Screpanti I, Gulino A. Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma. Neoplasia. 2011 Apr;13(4):374-85.
  3. Di Marcotullio L, Greco A, Mazzà D, Canettieri G, Pietrosanti L, Infante P, Coni S, Moretti M, De Smaele E, Ferretti E, Screpanti I, Gulino A. Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal. Oncogene. 2011 Jan 6;30(1):65-76.
  4. Sponziello ML, Bruno R, Durante C, D'Agostino M, Corradino R, Giannasio P, Ciociola E, Ferretti E, Maranghi M, Verrienti A, De Toma G, Filetti S, Russo D. Growth factor receptors gene expression and Akt phosphorylation in benign human thyroid nodules are unaffected by chronic thyrotropin suppression. Horm Metab Res. 2011 Jan;43(1):22-5
  5. Mancarelli MM, Zazzeroni F, Ciccocioppo L, Capece D, Po A, Murgo S, Di Camillo R, Rinaldi C, Ferretti E, Gulino A, Alesse E. The tumor suppressor gene KCTD11REN is regulated by Sp1 and methylation and its expression is reduced in tumors. Mol Cancer. 2010 Jun 30;9:172.
  6. Po A*, Ferretti E (* Equal contributors), Miele E, De Smaele E, Paganelli A, Canettieri G, Coni S, Di Marcotullio L, Biffoni M, Massimi L, Di Rocco C, Screpanti I, Gulino A. Hedgehog controls neural stem cells through p53-independent regulation of Nanog. EMBO J. 2010 Aug 4;29(15):2646-58
  7. De Smaele E, Ferretti E, Gulino A. Vismodegib, a small-molecule inhibitor of the hedgehog pathway for the treatment of advanced cancers. Curr Opin Investig Drugs. 2010 Jun;11(6):707-18. Review.
  8. Canettieri G, Di Marcotullio L, Greco A, Coni S, Antonucci L, Infante P, Pietrosanti L, De Smaele E, Ferretti E, Miele E, Pelloni M, De Simone G, Pedone EM, Gallinari P, Giorgi A, Steinkühler C, Vitagliano L, Pedone C, Schinin ME, Screpanti I, Gulino A. Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation. Nat Cell Biol. 2010 Feb;12(2):132-42.  
  1. De Smaele E, Ferretti E, Gulino A. MicroRNAs as biomarkers for CNS cancer and other disorders. Brain Res. 2010 Jun 18;1338:100-11.
  1. Sponziello M, Scipioni A, Durante C, Verrienti A, Maranghi M, Giacomelli L, Ferretti E, Celano M, Filetti S, Russo D. Regulation of sodium/iodide symporter and lactoperoxidase expression in four human breast cancer cell lines. J Endocrinol Invest. 2010 Jan;33(1):2-6.  
  1. Barnabei A, Ferretti E, Baldelli R, Procaccini A, Spriano G, Appetecchia M. Hurthle cell tumours of the thyroid. Personal experience and review of the literature. Acta Otorhinolaryngol Ital. 2009 Dec;29(6):305-11.
  2. Ferretti E, De Smaele E, Po A, Di Marcotullio L, Tosi E, Espinola MS, Di Rocco C, Riccardi R, Giangaspero F, Farcomeni A, Nofroni I, Laneve P, Gioia U, Caffarelli E, Bozzoni I, Screpanti I, Gulino A. MicroRNA profiling in human medulloblastoma. Int J Cancer. 2009 Feb 1;124(3):568-77.
  3. Gulino A, De Smaele E, Ferretti E. Glucocorticoids and neonatal brain injury: the Hedgehog connection. J Clin Invest. 2009 Feb;119(2):243-6.
  4. Gulino A, Ferretti E, De Smaele E. Hedgehog signalling in colon cancer and stem cells. EMBO Mol Med. 2009 Sep;1(6-7):300-2.
  5. Ianari A, Natale T, Calo E, Ferretti E, Alesse E, Screpanti I, Haigis K, Gulino A, Lees J (2009). Proapoptotic function of the retinoblastoma tumor suppressor protein. Cancer Cell. 2009 Mar 3;15(3):184-94.
  1. Celano M, Schenone S, Cosco D, Navarra M, Puxeddu E, Racanicchi L, Brullo C, Varano E, Alcaro S, Ferretti E, Botta G, Filetti S, Fresta M, Botta M, Russo D. Cytotoxic effects of a novel pyrazolopyrimidine derivative entrapped in liposomes in anaplastic thyroid cancer cells in vitro and in xenograft tumors in vivo. Endocr Relat Cancer. 2008 Jun;15(2): 499-510.
  2. De Smaele E, Fragomeli C, Ferretti E, Pelloni M, Po A, Canettieri G, Coni S, Di Marcotullio L, Greco A, Moretti M, Di Rocco C, Pazzaglia S, Maroder M, Screpanti I, Giannini G, Gulino A. An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma. Neoplasia. 2008 Jan;10(1):89-98.
  1. Ferretti E, De Smaele E, Miele E, Laneve P, Po A, Pelloni M, Paganelli A, Di Marcotullio L, Caffarelli E, Screpanti I, Bozzoni I, Gulino A. Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells. EMBO J. 2008 Oct 8;27(19): 2616-27.
  1. Ferretti E, Tosi E, Po A, Scipioni A, Morisi R, Espinola MS, Russo D, Durante C, Schlumberger M, Screpanti I, Filetti S, Gulino A. Notch signaling is involved in expression of thyrocyte differentiation markers and is down-regulated in thyroid tumors. J Clin Endocrinol Metab. 2008 Oct;93(10):4080-7.
  2. Gallo R, Grieco FA, Marselli L, Ferretti E, Gulino A, Marchetti P, Dotta F. Hedgehog signaling during expansion of human pancreatic islet-derived precursors. Ann N Y Acad Sci. 2008 Dec;1150:43-5.